Year: 2013 (December) Number: №4 Pages: 6-10
Heading: Organization and improvement of medical care and the state sanitary and epidemiological supervision. Prevention and liquidation of consequences of emergency situations.
Article type: Scientific article.
Authors: Olesov E.E., Kashchenko P.V., Pechenikhina V.S., Olesov A.E., Sobolev A.A.
Organization: FGBUZ «Clinical Center of Dentistry FMBA Russia», FGBOU DPO «Institute for Advanced Studies of FMBA of Russia».
The study of periodontal status and oral hygiene in 125 young workers NRC «Kurchatov Institute». The dynamics of hygiene and periodontal parameters in patients with poor oral hygiene during professional oral hygiene. In comparison with the dynamics of indicators in the absence of occupational calculated the financial costs and time for the normalization of periodontal status. Economic efficiency is defined twice within a year of occupational health.
Periodontal, occupational health, efficiency, economy.
Year: 2013 (December) Number: №4 Pages: 11-17
Heading: Organization and improvement of medical care and the state sanitary and epidemiological supervision. Prevention and liquidation of consequences of emergency situations.
Article type: Scientific article.
Authors: Fedina N.N., Makarov L.M., Komolyatova V.N., Kiseleva I.I.
Organization: Center for syncopal conditions and cardiac arrhythmias in children and adolescents FMBA of Russia at CCCH Federal Medical-Biological Agency.
One of the key factors for a balanced body functioning is balanced autonimic nervous system. Some 15 male professional athletes, high achievers, were examined (swimmers, football players, boat racers) age 17—25 (21±4), along with 2 groups, of relatively healthy males that ane not practicing any sports, 8 males in each group, group I — age 30—36 (33±3) and group II — age 83—89 (86±3). Every participant went through the Holter (ambulatory) monitoring (Medilog DARWIN 1.11.5, SCHILLER). Along with the Holter (ambulatory) monitoring, we analized vistual spectrum for the heart rate variability (the key function of the system). High frequency waves 0,15 to 0,40 HZ (HF — high freguence) had yellow and red coloring, showing parasympathetic effect on the heart rate; low frequency waves 0,04 to 0,15 HZ (LH — low freguence) had blue colour showing sympathetic effect on the heart rate. Group I, at night sleep, showed high level of parasympathetic tonicity (prevailed high frequency waves in red and yellow colour). Group II showed lesser deviations in circadian cycle caused by autonomic and parasympathetic effect on the heart rate (fewer high frequency waves in red and yellow colour). In 20% of athletes, at sleep it was found that parasympathetic NS has lesser effect on the heart rate (fewer high frequency waves in red and yellow colour) yet all 3 athletes were in pre-competition stressful training regiment. One week after the competition, with going back to the standard training regiment we observed prevalence of the high frequency waves in red and yellow colour — typical for automonic sleep regulation.
Conclusions: the spectrum analysis of autonomic heart rate regulation at night sleep in athletes helps to access the autonomic nervous system status and diagnose physical overstress (at various periods of training schedule) and to adjust it accordingly. In 20% of high achievements athletes, it was found autonomic sleep regulation was distorted at physical overstress. With age autonomic heart rate regulation becomes distorted, parasympathetic NS has lesser influence and autonomic regulation of circadian rythms is smoothing out.
Heart rate variability in athletes, sleep, holter monitoring, overtraining.
Year: 2013 (December) Number: №4 Pages: 18-22
Heading: Organization and improvement of medical care and the state sanitary and epidemiological supervision. Prevention and liquidation of consequences of emergency situations.
Article type: Scientific article.
Authors: Stoljarova S.A., Alekhnovich A.V., Afanasiev A.N.
Organization: Federal Governmental Budgetary Healthcare Institution «Central Children's Teaching Hospital FMBA of Russia».
Non-alcoholic fatty liver disease (NAFLD) has high prevalence in the world and is the main cause of chronic liver disease in children. The growth of disease is directly associated with increased frequency of obesity in the pediatric population. The key pathogenetic link in the development of NAFLD is Insulin resistance. The aim of this study was to evaluate the nature of insulin secretion and insulin sensitivity in adolescents with NAFLD. The results of the study in adolescents with NAFLD revealed change of indexes of insulin sensitivity: the decrease in Matsuda index and an increase in HOMA-IR index, indicating the presence of insulin resistance. Elevated levels of C-reactive protein is associated with insulin resistance and the degree of obesity.
Clinically obese, children, insulin resistance, nonalcoholic fatty liver disease.
Year: 2013 (December) Number: №4 Pages: 23-28
Heading: Organization and improvement of medical care and the state sanitary and epidemiological supervision. Prevention and liquidation of consequences of emergency situations.
Article type: Scientific article.
Authors: Shirshov V.N., Konstantinova I.M., Doronchuk D.N., Obolonkov V.Y., Shatirishvili O.K., Lebedev Y.I.
Organization: Federal Research Clinical Center of specialized types of healthcare and medical technologies under FMBA of Russia.
The article tells about the study of percutaneous surgery for coral shaped nephrolithiasis. It highlights the cornerstone points of nephrolitholopaxy. The study presents benefits and weak points of this kind of treatment, complications and results in group of 107 patients. The article reflects the recent points of view on this pathology of other urologists.
Percutaneous surgery, coral shaped nephrolithiasis.
Year: 2013 (December) Number: №4 Pages: 29-40
Heading: Organization and improvement of medical care and the state sanitary and epidemiological supervision. Prevention and liquidation of consequences of emergency situations.
Article type: Scientific article.
Authors: Ivanov Y.V., Alekhnovich A.V., Dyatchina G.V., Solovjev N.A., Zlobin A.I.
Organization: Federal state institution «Federal scientific-clinical center of specialized medical care and medical technology» of the Federal medical-biological Agency of Russia.
Presents the results of complex treatment of patients with necrotizing pancreatitis using traditional laparotomic, endoscopic and transcutaneus interventions. It is proved that adequate prophylaxis and drainage of the wounds, combined with a limited surgical intervention with minimally invasive procedures provide advantages in comparison with the results of the treatment with traditional methods in the early stage of the disease when purulent complications are limited. The use of minimally invasive technologies in a complex with conservative treatment of patients with necrotizing pancreatitis helps to enhance the detoxification, stabilize the condition of the patients and perform, if necessary, open surgeries in more favorable conditions.
Necrotizing pancreatitis, minimally invasive surgical techniques, videolaparoscopiya, transcutaneus drainage, mini-laparotomic access, pancreas.
Year: 2013 (December) Number: №4 Pages: 47-54
Heading: The results of research works in the field of studying the influence on the humans especially dangerous and harmful production factors.
Article type: Scientific article.
Authors: Filippov V. L., Rembovskiy V. R., Filippova Yu. V., Medvedev D.S.
Organization: Research Institute of Hygiene, Occupational Pathology and Human Ecology Federal State Unitary Enterprise, Federal Medical Biological Agency of Russia.
Objective: to demonstrate the need for an immediate implementation of the concepts of WHO and ILO on occupational health and safety and prioritization of medical aid due to urgent measures aimed to protect mental health of employees working with highly hazardous toxic substances.
Materials and methods: the analysis of documents of WHO and ILO. Using clinical-psychopathological method we examined group of employees working with highly hazardous toxic substances.
Conclusions: we have considered various approaches to implement WHO and the ILO concepts of occupational health and safety. Was shown the importance of mental health problems of the employees working with highly hazardous toxic chemicals. Special attention was drawn to stress associated with the work conditions, in particular — mobbing. Considering complicated habitat conditions of employees working in extreme conditions, we paid special attention to the crucial role of mental health, psycho-diagnostics and psychoprophylaxis. Facing the challenges of the XXI century the importance of mental health remains one of the key priorities. Measures helping in prevention of mental health issues among employees working with highly hazardous toxic substances, have to be prompt and sufficient.
Mental health, diagnostics, toxic and hazardous chemicals.
Year: 2013 (December) Number: №4 Pages: 56-64
Heading: The results of research works in the field of studying the influence on the humans especially dangerous and harmful production factors.
Article type: Scientific article.
Authors: Sibiryakov V.K., Ivanenko A.A., Malov A.V., Rutkovsky G.V., Goryaeva L.I.
Organization: «Institute of toxicology» of Federal Medico-Biological Agency, Federal State Unitary Enterprise «The Ural Research Institute for Metrology».
The new blood Certified Reference Material (CRM) for cadmium was prepared as apart of a corresponding contract task with framework of the state program «Chemical Safety of Russia». Material basis ofCRM was the bovine blood in which the necessary amount of cadmium salt has been added. Lyophilization was the basic of preparation of the dry stable homogenous reference material of blood containing cadmium. Procedure of the state certification CRM has been executed in Federal State Unitary Enterprise «The Ural Research Institute for Metrology», in Yekaterinburg. The new CRM has the certificate of the state registration № 10128-2012.
Cadmium, blood, crm, homogeneity, stability, the state registration.
Year: 2013 (December) Number: №4 Pages: 65-69
Heading: The results of research works in the field of studying the influence on the humans especially dangerous and harmful production factors.
Article type: Scientific article.
Authors: Kudryavtseva G.A.
Organization: Federal State Unitary Enterprise «Research Institute for Hygiene, Toxicology and Occupational Pathology» at Federal Medical and Biological Agency.
Objective. To identify the characteristics of circadian dynamics in animals with different levels of general non-specific reactivity, exposed to stress stimulus.
Materials and Methods. The study included 60 guinea pigs of both genders with body weight 300—350g. We assessed the level of general non-specific reactivity of the body within 24 hours after intraperitoneal injection of lipopolysaccharide S. Thyphimurium (LPS) — 0.5 mg/kg. We measured auricular body temperature in °C within the first 30 min after administration of the toxin (ΔT30) and followed the dynamic of leukocytes count for the first 180 minutes after administration of LPS (ΔL180).
Results. Performed experimental studies showed dependence of the circadian organization of individual physiological parameters of laboratory animals with the daily cycle of activity on the level
of general nonspecific reactivity. Obtained evidence concerned such integrated indicators of life activity, body temperature and white blood cell count in the peripheral blood.
Conclusion. The experimental exposure to bacterial LPS caused stereotyped responses: increase of the body temperature by 0, 8—1, 8 °С, lower leukocytes count by 40%. For the 24 hours rhythm of these reactions, acrophase between 12.00—15.00 and amplitudes ranging from 20 to 80 % of mezora were typical. Animals with a high level of general non-specific reactivity show specific characteristics of circadian organization in response to stressful stimuli forming later and larger in amplitude rhythms. For the daily rhythms of animals with low Exactly general non-specific reactivity have smaller amplitudes and relative to earlier acrophase of temperature and contents of leukocytes in the blood. Thus, it can be concluded that the strength and circadian variability of these reactions differ in the experimental groups, depending on the characteristics of the circadian organization of life and functional status in animals with a different level of general non-specific reactivity.
Circadian biorhythms, functional state of the overall level of non-specific reactivity of the body.